Thorne Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - 90 Capsules

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Young-Sung, K., et al. (2020). Neuroprotective effects of magnesium L-threonate in a hypoxic zebrafish model. According to World Health Organization statistics, as many as 75 percent of U.S. adults do not meet the U.S. Food and Drug Administration’s Recommended Daily Intake of 420 mg of magnesium. Magnesium deficiency can manifest in many ways, such as inefficient blood sugar metabolism, muscle cramps or soreness, eyelid twitching, fatigue, and poor sleep.* People who suffer from migraines: While it is still a new area of research, it has been found that people who suffer from migraine headaches may have a lower level of magnesium in their blood and tissues when compared to those who do not suffer from migraines. The American Academy of Neurology and the American Headache Society now provide evidence-based guidelines stating that magnesium therapy may be effective for migraine prevention under the supervision of a healthcare provider. “Magnesium, in particular magnesium oxide, has also been studied in migraine headaches as an effective preventative nutraceutical,” states Ann Ming Yeh, MD.

At 150 milligrams per capsule, Pure Encapsulations Magnesium Citrate can be a good option to treat a magnesium deficiency or constipation when directed by a healthcare professional. Typical side effects of magnesium citrate include cramping, gas, and nausea, so be on the lookout for those and share any issues with a healthcare provider. If you are magnesium deficient or have a health condition that puts you at risk for deficiency, a magnesium supplement may be beneficial. Selecting the most suitable form of magnesium, as well as the appropriate dosage, is an essential step in choosing the right product for you. According to McGregor, it's usually better to take a magnesium supplement later in the day, particularly if you're using it to help with sleep. She also says to consider the other nutrients that you're taking it with – magnesium competes with calcium for uptake in the body, for example.Karimi N, et al. (2021). The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study. Wang J, Liu Y, Zhou LJ, et al. Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-α. Pain Physician. 2013;16(5):E563-E575. USDA, Agricultural Research Service, 2019. Usual Nutrient Intake from Food and Beverages, by Gender and Age, What We Eat in America, NHANES 2013-2016 Available http://www.ars.usda.gov/nea/bhnrc/fsrg Promotes the dilation of blood vessels (vasodilation), which supports normal blood pressure and enhances blood flow*

Manufacturers claim that using acetyl-L-carnitine supplements can help with memory and feelings of alertness. Some research indicates that ginkgo supplements can help slow age-related cognitive decline and improve memory and thinking skills. However, overall, the results from studies evaluating its effects are mixed. Pure Encapsulations Magnesium tops our list because it is from a trusted, third-party-tested brand and contains a preferable form of magnesium. Magnesium glycinate typically has increased tolerability and absorption because the magnesium is bound to the amino acid glycine. This makes magnesium in a chelated form, which can get absorbed better in the intestine.Magnesium L-threonate: Studied for cognitive health due to its ability to cross the blood-brain barrier. Another sign of low magnesium levels, particularly in women who are perimenopausal or menopausal, is poor sleep, says McGregor. We all also lose magnesium through our sweat, so you might notice that your levels are lower in the warmer months compared with the colder ones.